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The pharmaceutical industry is made up of companies that research, develop, make, and sell drugs and treatments used to treat or eradicate diseases and vaccinate people. This includes some of the largest and best-known companies in the world, such as Pfizer Inc., Merck & Co., and AbbVie Inc. A number of pharmaceutical companies have experienced a surge in their sales after winning approval from U.S. and other governments for vaccines aimed at protecting people against the COVID-19 virus.
Over the past 12 months, pharmaceutical stocks, based on the iShares U.S. Pharmaceuticals ETF (IHE), have outperformed the overall market. IHE’s total return over the period was -2.6%, compared with the S&P 500’s total return of -9.8%. These market performance figures and all statistics in the tables below are as of Sept. 14, 2022.
Here are the top three pharmaceutical stocks in each category: best value, the fastest growth, and the most momentum.
Best-Value Pharmaceutical Stocks
These are the pharmaceutical stocks with the lowest 12-month trailing price-to-earnings (P/E) ratio. Because profits can be returned to shareholders in the form of dividends and buybacks, a low P/E ratio shows you’re paying less for each dollar of profit generated.
Price ($)
Market Cap ($B)
12-Month Trailing P/E Ratio
Embecta Corp. (EMBC)
32.50
1.9
5.5
Organogenesis Holdings Inc. (ORGO)
3.55
0.5
6.4
Organon & Co. (OGN)
28.62
7.3
6.6
Source: YCharts
Embecta Corp.: Embecta is a diabetes care company that makes medical devices. The company offers pen needles, syringes, and safety devices to help people manage diabetes. Embecta only recently became an independently traded public company. On April 1, the company announced that it had completed its spinoff from Becton, Dickinson & Co., also known as BD.
Organogenesis Holdings Inc.: Organogenesis Holdings is a holding company that, through subsidiaries, develops and manufactures products used for advanced wound care and in the surgical and sports medicine industries. On Aug. 15, the company announced that it had received clearance from the U.S. Food and Drug Administration (FDA) for PuraPly MZ. PuraPly MZ is a brand extension of the pre-existing PuraPly brand and consists of a powdered product used to address complex surgical wounds.
Organon & Co.: Organon is a global women’s health-care company that develops and produces medicines and other products across a range of areas, including reproductive health, heart disease, immunology, oncology, and dermatology.
Fastest-Growing Pharmaceutical Stocks
These are the top pharmaceutical stocks as ranked by a growth model that scores companies based on a 50/50 weighting of their most recent quarterly YOY percentage revenue growth and their most recent quarterly YOY earnings-per-share (EPS) growth. Both sales and earnings are critical factors in the success of a company. Therefore, ranking companies by only one growth metric makes a ranking susceptible to the accounting anomalies of that quarter (such as changes in tax law or restructuring costs) that may make one or the other figure unrepresentative of the business in general. Companies with quarterly EPS or revenue growth of more than 2,500% were excluded as outliers.
Price ($)
Market Cap ($B)
EPS Growth (%)
Revenue Growth (%)
SNDL Inc. (SNDL)
2.80
0.7
N/A (see company description)
2,250
Intra-Cellular Therapies Inc. (ITCI)
50.15
4.7
N/A (see company description)
189.8
Merck & Co. (MRK)
86.95
220.3
154.1
28.0
Source: YCharts
SNDL Inc.: SNDL is a Canada-based medical and adult-use cannabis producer. The company operates cultivation and processing facilities, retail stores, and also sells alcoholic beverages. The company announced on Aug. 22 that it would acquire cannabis product manufacturer Valens Co. (VLNS) for total consideration of about $138 million. The deal is expected to close in January 2023. SNDL had negative EPS for the most recent quarter, so it does not have an EPS growth figure in the table above.
Intra-Cellular Therapies Inc.: Intra-Cellular Therapies is a biopharmaceutical company that develops and markets treatments for people living with complex psychiatric and neurologic diseases. The company reported Q2 2022 earnings on Aug. 9. Net losses widened as revenue nearly tripled YOY. Intra-Cellular said that “strong uptake in bipolar depression” contributed to revenue growth. The company had negative EPS for the most recent quarter, so it does not have an EPS growth figure in the table above.
Merck & Co. : Merck & Co. is a global healthcare company which provides prescription medicines, biologic therapies, vaccines, and animal health products.
Pharmaceutical Stocks With the Most Momentum
These are the three pharmaceutical stocks that had the highest total return over the past 12 months.
Price ($)
Market Cap ($B)
12-Month Trailing Total Return (%)
Lantheus Holdings Inc. (LNTH)
86.05
5.9
250.1
SIGA Technologies Inc. (SIGA)
13.20
1.0
113.8
Amphastar Pharmaceuticals Inc. (AMPH)
29.62
1.5
64.7
S&P 500
N/A
N/A
-9.8
iShares U.S. Pharmaceuticals ETF (IHE)
N/A
N/A
-2.6
Source: YCharts
Lantheus Holdings Inc.: Lantheus is a holding company that operates through subsidiaries, including Lantheus Medical Imaging and Progenics Pharmaceuticals. The company offers diagnostics, targeted therapeutics, and artificial intelligence solutions used to detect and evaluate a variety of diseases and conditions.SIGA Technologies Inc.: SIGA Technologies is a commercial-stage pharmaceutical company. It is focused on health and security, which includes developing countermeasures for biological and chemical attacks as well as vaccines and therapies for emerging infectious diseases.Amphastar Pharmaceuticals Inc.: Amphastar Pharmaceuticals is a biopharmaceutical company that develops, manufactures, and sells generic and injectable, inhalation, and intranasal products. It also sells an insulin-active pharmaceutical ingredient. In mid-August, Amphastar reported that its New Drug Application for Epinephrine pre-filled syringes had been approved by the FDA. Epinephrine injection is used in certain patients experiencing septic shock.
The comments, opinions, and analyses expressed herein are for informational purposes only and should not be considered individual investment advice or recommendations to invest in any security or to adopt any investment strategy. Though we believe the information provided herein is reliable, we do not warrant its accuracy or completeness. The views and strategies described in our content may not be suitable for all investors. Because market and economic conditions are subject to rapid change, all comments, opinions, and analyses contained within our content are rendered as of the date of the posting and may change without notice. The material is not intended as a complete analysis of every material fact regarding any country, region, market, industry, investment, or strategy.
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